is a Scottish professional footballer who plays as a midfielder for and captains Arsenal of the English Women's Super League. Before her retirement from international duty in 2021, Little was vice-captain of the Scotland national team. She began her senior career at Hibernian, winning the Scottish Premier League, Scottish Women's Cup and Scottish Premier League Cup with the club in the 2006–2007 season. With Arsenal, she is a two time Premier League National Division winner, five time League Cup winner, three time Women's Super League and FA Cup winner, and a Champions League winner. During her time at Seattle Reign, Little won the Golden Boot and Most Valuable Player awards.

Little began representing Scotland at the senior international level in 2007 at age 16, scoring Scotland's first hat trick in 2012, and helping them qualify for Euro 2017 and the 2019 World Cup. She was one of two Scots selected for the Great Britain squad that reached the quarterfinals of the 2012 London Olympics, and again at the delayed 2020 Tokyo Olympics.

In 2010, she was named the FA's Women's Player of the Year. In 2013, she became the first recipient of the PFA Women's Players' Player of the Year award. In 2016, she was named BBC Women's Footballer of the Year after being nominated for the second consecutive year. Since 2019, Little has been named in the PFA WSL Team of the Year three times.

In 2025, Little captained Arsenal to win the UEFA Women's Champions League for the clubs second time and first in eighteen years. She is one of only two Scottish women's football players to have ever won the UWCL.