Botafogo de Futebol e Regatas (Brazilian Portuguese pronunciation: [bɔtaˈfoɡu dʒi futʃiˈbɔw i ʁeˈɡatɐs]; Botafogo Football and Rowing) is a Brazilian sports club based in the neighborhood of Botafogo, in the city of Rio de Janeiro. Although it competes in a number of different sports, Botafogo is mostly known for its association football team. It plays in the Campeonato Brasileiro Série A, the top tier of the Brazilian football league system, and in the state of Rio de Janeiro's premier state league.

The club is among Brazil's \"Big 12 Clubs\" having won the Brazilian Championship three times (1968, 1995, 2024), the Copa Libertadores in 2024, and the Copa CONMEBOL in 1993. In addition, the Botafogo de Futebol e Regatas has some of Brazilian football's most notable records, including most unbeaten matches: 52 games between 1977 and 1978; the most unbeaten matches in the Brazilian Championship: 42, also between 1977 and 1978; and the most players called up to the Brazilian national team in World Cups. The club holds the record for the greatest victory ever recorded in Brazilian football: 24–0 against Sport Club Mangueira in 1909.

In 2000, Botafogo finished 12th in a vote by subscribers of FIFA Magazine for the FIFA Club of the Century. In 2024, Botafogo was recognized by the IFFHS as the Best Club in South America and the 5th Best Club in the World.