Club Independiente Santa Fe, known simply as Santa Fe, is a Colombian professional football team based in Bogotá, that currently plays in the Categoría Primera A. They play their home games at the El Campín stadium. Santa Fe is one of the three most successful teams in Colombia, winning eighteen titles, which include nine national championships (most recently in 2016), four Superliga Colombiana, two Copas Colombia, and international titles such as one Copa Sudamericana, one Suruga Bank Championship, and one Copa Simón Bolívar. Santa Fe is one of the three clubs that has played every championship in the Categoría Primera A.

Santa Fe became the first Colombian team to win the Copa Sudamericana, and the first and only Colombian team to win an official tournament outside America. The club was recognized as one of the ten best clubs in the world in 2015 by the IFFHS, occupying the seventh position and being the best ranked of South America.

Santa Fe has a fierce rivalry with Millonarios who share the same stadium. The game is considered one of the most famous derbies in South America and is known as El Clásico Bogotano or El Clásico Capitalino.