Club de Futbol Cruz Azul S.A. de C.V., commonly referred to as Cruz Azul, is a professional football club based in Mexico City, Mexico. It competes in Liga MX, the top tier of Mexican football. Founded in 1927 in Jasso, Hidalgo, as Club Deportivo, Social y Cultural Cruz Azul A.C., the club officially moved to Mexico City in 1971, where it had already registered a great presence and activity since its beginnings. The team changed its name to Cruz Azul Fútbol Club, A.C. in 2012 and later to its current name in 2022. Since 2025, Cruz Azul has played its home matches at the Estadio Olímpico Universitario, due to renovations at the Estadio Azteca for the 2026 FIFA World Cup. Its headquarters are in La Noria, a suburb within Xochimilco in the southern part of Mexico City.

Domestically, the club has won nine league titles, four Copa MX, three Campeón de Campeones, and holds a joint-record with one Supercopa de la Liga MX and one Supercopa MX. In international competitions, the club's seven titles make it the joint-record most successful club in the history of the CONCACAF Champions Cup/Champions League, the most prestigious international club competition in North American football. Cruz Azul also holds numerous distinctions, including being the club with the most league runner-up finishes (12), the first CONCACAF team to reach the final of the Copa Libertadores—the most prestigious club competition in South American football—losing on penalties to Boca Juniors in 2001, achieving the continental treble in the 1968–69 season by winning the Primera División, Copa México and CONCACAF Champions' Cup titles, becoming the first CONCACAF club and third worldwide to accomplish this feat, and becoming the first club worldwide, and one of only five, to have won the continental treble twice.

In its 2014 Club World Ranking, the International Federation of Football History & Statistics placed Cruz Azul as the 99th-best club in the world and the third-best club in CONCACAF. According to several polls, Cruz Azul is the third-most popular team in Mexico, behind only Guadalajara and América. It is also the second most supported team in its area, Greater Mexico City, behind América and ahead of Pumas UNAM. Together, these clubs are considered the \"Big Four\" (Cuatro Grandes) of Mexican football, due to their historical success, large fan bases, and intense rivalries.