Vitória Sport Clube, popularly known as Vitória de Guimarães or sometimes just Vitória, is a Portuguese professional football club based in Guimarães that competes in the Primeira Liga, the top flight of Portuguese football, at the Estádio D. Afonso Henriques. The club also stands out on the national and international scene in sports such as athletics, volleyball, basketball, handball, water polo, swimming, jiu-jitsu, taekwondo and kickboxing, among others.

It is currently the 4th club with the most appearances, totalling 81 participations, at the top level of the sport in Portugal. It's also the 4th club with the most members, around 39,000, and it's also the 4th club with the best average stadium attendance in Portugal, well ahead of its direct rivals.

Vitória de Guimarães have finished third in the Primeira Liga on four occasions, most recently in 2007–08. They have won one Taça de Portugal in 2012–13 and one Supertaça Cândido de Oliveira in 1988, while also being runners-up of the former on six occasions.

The club have competed regularly in European competitions, where their best finish was the quarter-finals of the 1986–87 UEFA Cup.

Vitória SC have a long-standing rivalry with nearby club SC Braga, with whom they contest the Minho derby. In addition to this age-old rivalry, Vitória has another major dispute with Boavista FC from the city of Porto.