Clube Desportivo Nacional (Portuguese pronunciation: [nɐsjuˈnal dɐ mɐˈðɐjɾɐ]), commonly known as Nacional da Madeira and sometimes just Nacional, is a Portuguese football club based in Funchal, on the island of Madeira.

Founded on 8 December 1910, it currently plays in the Liga Portugal , Portugal's top-tier division of professional football. It plays its home games at Estádio da Madeira, also known as Estádio da Choupana. Built in 1998 and named at the time Estádio Eng. Rui Alves after the current club president Rui Alves, it seats approximately 5,200 people. The stadium is located in the north of Funchal, high in the mountains of the Choupana district. The club's home colours are black and white striped shirts with black shorts and socks. Nacional is also known for being one of the clubs that formed Portuguese international Cristiano Ronaldo and to honour the club's most famous player they named their youth training facilities Cristiano Ronaldo Câmpus Futebol.

The Alvinegros played in the Primeira Liga in 1988–91, 2002–17, 2018–19 and 2020–21. Their best top-tier league finish was fourth in the 2003–04 and 2008–09 seasons, with Brazilian striker Nenê winning the Bola da Prata for top scorer with 20 goals in the latter. They have played in the UEFA Europa League on five occasions between 2004 and 2014, beating Zenit St. Petersburg in the play-off round and taking third place in the group stage in 2009–10. The team has reached the Taça de Portugal semi-finals four times between 2009 and 2023, and the Taça da Liga semi-final in 2010–11. Notable managers include Manuel Machado, who led the team in five spells from 2005 to 2021. They currently play in Primera Liga, after they got promoted from the 2023–24 Liga Portugal 2.

Like many other Portuguese clubs, Nacional operates several sports teams outside the football team. Other sports groups within the organisation include beach soccer, boxing, artistic gymnastics, rhythmic gymnastics, tennis, triathlon, muay thai, padel, rallying, swimming and veterans' soccer.