Adana Demirspor Kulübü is a multi-sports club based in Adana, Turkey. The football department is the most popular department which relegated to TFF 1. Lig on 16 March 2025 after 4 seasons at the Super Lig.

Founded by railway workers of Turkish State Railways (TCDD) in 1940, The football team's success at the Adana League and the water polo team's unbeaten National League titles in the club's first three decades built a large worker fan base in the city. Some supporters who are unhappy with the management of the club, founded Adanaspor in 1954 and competition among the two clubs for the citywide support and domination since then, created one of the fiercest rivalries of Turkish football which continues to this day as the Adana derby.

Adana Demirspor was the first club based outside of Istanbul, Ankara, or İzmir to join the National Football League in the 1960–61 season, before this the league games were only hosted in the three cities. The water polo team was the first champions of the Turkish Water Polo League and had dominated the first three decades of the league, winning 21 league titles in 25 years, from the early 1940s to mid 1960s.

Adana Demirspor are by far the most successful of the 38 Demirspor clubs that are founded by the employees of the Turkish State Railways (TCDD). Most Demirspor clubs have jersey colours identical to Adana Demirspor, and bear the TCDD symbol on their logo. Ankara Demirspor are the only other Demirspor club that compete in the Turkish professional football league system, and the only ones still affiliated with the TCDD.