, commonly known as Isco ([ˈisko]), is a Spanish professional footballer who plays as an attacking midfielder or left winger for La Liga club Real Betis, which he captains and the Spain national team.

Isco began his career at Valencia, playing mainly in its reserve team, before joining Málaga in 2011. His performances at Málaga earned him the Golden Boy award in 2012, and a €65 million move to Real Madrid in June 2013, with whom he won 27 major trophies including five UEFA Champions League titles, three La Liga titles, one Copa del Rey and four FIFA Club World Cup titles.

Isco represented Spain at various youth levels, including at the 2012 Olympics, and made his senior international debut in 2013, later taking part at the 2018 FIFA World Cup.